Deficient activity of FAD-linked glycerophosphate dehydrogenase in islets of GK rats
نویسندگان
چکیده
منابع مشابه
Hexose metabolism in pancreatic islets. Glucose-induced and Ca(2+)-dependent activation of FAD-glycerophosphate dehydrogenase.
A rise in extracellular D-glucose concentration causes in pancreatic islets a preferential stimulation of aerobic, relative to total, glycolysis. The possible participation in such a phenomenon of a glucose-induced and Ca(2+)-dependent activation of FAD-glycerophosphate dehydrogenase was investigated. In islet homogenates, the activity of the mitochondrial and Ca(2+)-responsive FAD-glycerophosp...
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15 صفحه اولInduction of hepatic mitochondrial glycerophosphate dehydrogenase in rats by dehydroepiandrosterone.
Feeding the thermogenic steroid, 5-androsten-3 beta-ol-17-one (dehydroepiandrosterone, DHEA) in the diet of rats induced the synthesis of liver mitochondrial sn-glycerol 3-phosphate dehydrogenase to levels three to five times that of control rats within 7 days. The previously reported enhancement of liver cytosolic malic enzyme was confirmed. The induction of both enzymes was detectable at 0.01...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 1993
ISSN: 0012-186X,1432-0428
DOI: 10.1007/bf00401142